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Guice, LSU rout Missouri to win Orgeron's debut (0:54)

Filling in for Leonard Fournette, Derrius Guice rushes for 163 yards and three touchdowns as LSU wins Ed Orgeron's debut as head coach with a 42-7 victory over Missouri. (0:54)

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Breaking down LSU's dominant rushing attack without Leonard Fournette (1:50)

Breaking down LSU's dominant rushing attack without Leonard Fournette (1:50)

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LSU embraces change in win over Mizzou (1:37)

LSU running back Derrius Guice discusses the 42-7 win over Missouri and the changes under coach Orgeron. (1:37)

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Orgeron: 'We're just getting started' (1:17)

Tigers head coach Ed Orgeron gives his thoughts on his LSU head coaching debut and his team's 42-7 win over Mizzou. (1:17)

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Interim head coach Ed Orgeron gets a gatorade bath after LSU's dominant 42-7 win over Missouri (0:20)

Interim head coach Ed Orgeron gets a gatorade bath after LSU's 42-7 win over Missouri (0:20)

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Darrel Williams becomes the second LSU player with three rushing TD's on the day (0:43)

Darrel Williams run for 9 yds for a TD (0:43)

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Missouri gets on the board with reverse pass to QB Lock (0:46)

Bringing out the reverse WR Eric Laurent pass to QB Drew Lock in the end zone gets Missouri on the board against LSU. (0:46)

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D. Williams run for 2-yards for a TD (0:36)

Darrel Williams run for 2 yds for a TD (0:36)

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LSU receiver wins battle of tipped pass (1:30)

Danny Etling pass complete to D.J. Chark for 41 yds to the Misso 32 for a 1ST down (1:30)

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Missouri's Brandon Lee ejected for targeting (1:45)

Danny Etling pass complete to Jazz Ferguson for 7 yds to the MISSOURI 48 for a 1ST down MISSOURI Penalty, Personal Foul (Brandon Lee) to the Misso 33 for a 1ST down (1:45)

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D. Williams run for 1-yard for a TD (1:00)

Darrel Williams run for 1 yd for a TD (1:00)

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Missouri and LSU benches scuffle at the end of the half (0:59)

Missouri and LSU benches scuffle at the end of the half (0:59)

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LSU's Guice makes it a hat trick of TD's in the first half (1:20)

Playing without the injured Leonard Fournette, Derrius Guice steps up big time scoring his third touchdown of the game, this time from 37 yards out. (1:20)

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D. Guice run for 4-yards for a TD (0:55)

Derrius Guice run for 4 yds for a TD (0:55)

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D. Lock pass intercepted by T. White (0:53)

Drew Lock pass intercepted Tre'Davious White return for no gain to the LSU 11 (0:53)