Bryant hurt his right shoulder in the first quarter of last week's game against the Tennessee Titans, but he was able to return and finished with 10 catches for 103 yards and a touchdown. He did not practice Wednesday and was limited in workouts Thursday and Friday.
He has played in 42 straight games after missing five of the first 18 games of his career.
On Thursday, Bryant said the shoulder was "a little bit sore, but nothing that's going to keep me out. I'm going to be ready to roll on Sunday."
Linebacker Rolando McClain is doubtful but did not practice this week with a groin injury. If he can't play, then the Cowboys will move rookie Anthony Hitchens to the middle with Bruce Carter (weak side) and Kyle Wilber (strong side) handling the outside linebacker spots.
"It's not my decision," McClain said. "It's coach's decision. I'll just do whatever he'll ask me to do and we'll go from there."
Quarterback Tony Romo (back) went through his second straight full practice after sitting out of Wednesday's practice with tightness in his back. He is listed as probable.
Tight end Gavin Escobar (knee), running back Joseph Randle (concussion) and defensive end Lavar Edwards (knee) are also questionable. Randle practiced for the first time Friday and was limited after passing the league's concussion protocol.