To help you set your lineups and avoid starting a player who won't take the field, we will post fantasy-relevant updates and analysis here as NFL teams release their inactives lists, typically about 90 minutes before kickoff. Any rankings cited in this column come from our ESPN Fantasy staff ranks.
Refresh often for the latest information.
4 p.m. ET games
Damien Williams, RB, KC: Ribs -- OUT
Impact: Combine this news with Darrel Williams getting placed on IR, and Darwin Thompson might jump into fantasy relevance.
Julian Edelman, WR, NE: Shoulder -- Active
Impact: Nothing to see here. Edelman will play, as usual.
Mohamed Sanu Sr., WR, NE: Ankle -- Active
Impact: Neither N'Keal Harry nor Phillip Dorsett II has done much to eat into Sanu's production.
Josh Jacobs, RB, OAK: Shoulder -- Inactive
Impact: DeAndre Washington and Jalen Richard should both have increased fantasy value.
Hunter Renfrow, WR, OAK: Ribs -- OUT
Impact: It's unclear how long he'll be out. Look to other teams for WR replacements.
James Conner, RB, PIT: Shoulder -- OUT
Impact: Benny Snell Jr. once again should get the majority of carries in this backfield.
JuJu Smith-Schuster, WR, PIT: Knee -- OUT
Impact: James Washington/Diontae Johnson get slight upticks in value.
Adam Humphries, WR, TEN: Ankle -- OUT
Impact: In what should be a good matchup, A.J. Brown should get the bulk of targets.
Tajae Sharpe, WR, TEN: Hamstring -- Active
Impact: Corey Davis may step up if Sharpe is limited.
Byron Murphy Jr., CB, ARI: Calf -- Active
Jalen Thompson, CB, ARI: Concussion -- Active
Ronnie Harrison, S, JAX: Concussion -- Inactive
Frank Clark, DE, KC: Shoulder -- Active
Patrick Chung, S, NE: Heel -- Active
Jason McCourty, CB, NE: Groin -- Active
LeShaun Sims, CB, TEN: Ankle -- OUT
Official Sunday inactives should begin coming in at approximately 11:30 a.m. ET for the early games and 2:30 p.m. ET for the late games.
1 p.m. ET games
Seth Roberts, WR, BAL: Knee -- Active
Impact: Participated fully on Friday, so should be able to go a full 60 minutes.
Marquise Brown, WR, BAL: Ankle -- Active
Impact: He's been banged up all season long but has consistently managed to stay in the huddle.
Greg Olsen, TE, CAR: Concussion -- OUT
Impact: Ian Thomas the most likely of the potential replacements to shine.
A.J. Green, WR, CIN: Ankle -- OUT
Impact: Surprise! Or not.
Demetrius Harris, TE, CLE: Shoulder -- Inactive
Impact: David Njoku is back from IR, so he will take over some targets here.
Matthew Stafford, QB, DET: Back -- OUT
Impact: David Blough will get a chance to start, with Jeff Driskel on IR.
T.J. Hockenson, TE, DET: Ankle -- OUT/IR
Impact: Jesse James/Logan Thomas to handle TE duties.
Will Fuller V, WR, HOU: Hamstring -- Inactive
Impact: Lack of practice time this week would have made him a risky option for the fantasy playoffs anyway.
T.Y. Hilton, WR, IND: Calf -- OUT
Impact: Parris Campbell (hand) is expected to play. If you're a postseason underdog, you might want to chance it.
Adam Vinatieri, K, IND: Knee -- OUT
Impact: Waiver-wire man on the move Chase McLaughlin will replace the veteran.
Adam Thielen, WR, MIN: Hamstring -- Inactive
Impact: Not surprising, as he didn't practice all week. Bisi Johnson's value rises a bit.
Le'Veon Bell, RB, NYJ: Illness -- OUT
Impact: Bilal Powell will get some extra totes, with Ty Montgomery offering change-of-pace duties.
Demaryius Thomas, WR, NYJ: Hamstring -- Active
Impact: Limited all week, but will be on the field, as expected.
Ryan Griffin, TE, NYJ: Illness -- Active
Impact: Game-time call, but the ailment has apparently passed. He should get some points.
Marquise Goodwin, WR, SF: Knee -- Inactive
Impact: He is still behind the 49ers' top trio of WR options, so no use hanging on to him.
Dante Pettis, WR, SF: Knee -- Inactive
Impact: See comment above.
Scotty Miller, WR, TB: Hamstring -- OUT
Impact: Breshad Perriman had a strong Week 13 filling in here. History may well repeat.
Paul Richardson Jr., WR, WAS: Hamstring -- OUT
Impact: Kelvin Harmon gets minor bump in value.
Trey Quinn, WR, WAS: Concussion -- OUT
Impact: Steven Sims Jr. could get a few catches.
Patrick Onwuasor, L, BAL: Ankle -- Active
Marlon Humphrey, CB, BAL: Thigh -- Active
Mario Addison, DE, CAR: Groin -- Active
Sam Hubbard, DE, CIN: Knee -- OUT
Olivier Vernon, DE, CLE: Knee -- Inactive
Von Miller, LB, DEN: Knee -- Active
Malik Reed, L, DEN: Ankle -- Inactive
Kevin King, CB, GB: Shoulder -- Inactive
Brennan Scarlett, L, HOU: Shoulder -- Active
Bradley Roby, CB, HOU: Hamstring -- Active
Kenny Moore II, CB, IND: Ankle -- OUT
Malik Hooker, S, IND: Foot -- Active
Rock Ya-Sin, CB, IND: Ankle -- Active
Kiko Alonso, LB, NO: Thigh -- OUT
A.J. Klein, LB, NO: Knee -- OUT
Steve McLendon, DT, NYJ: Knee -- Active
Henry Anderson, DE, NYJ: Shoulder -- Active
Jamal Adams, S, NYJ: Ankle -- Inactive
Jaquiski Tartt, S, SF: Ribs -- OUT