Who should you start? Who should you sit? To help you set your fantasy football lineups and to avoid starting a player who won't be in the lineup, we'll post fantasy-relevant updates and analysis here as NFL teams release their inactives, typically about 90 minutes before kickoff. Any rankings cited in this column come from our ESPN Fantasy staff ranks.
Refresh often for the latest information.
Sunday night game
Miles Sanders, RB, PHI: Knee -- OUT
Impact: Boston Scott takes over as the team's No. 1 RB.
DeSean Jackson, WR, PHI: Ankle -- OUT
Impact: Alshon Jeffery/Jalen Reagor to start for the Eagles at WR.
Dallas Goedert, TE, PHI: Ankle -- OUT
Impact: Zach Ertz will handle the majority of TE targets ...
Richard Rodgers, TE, PHI: Calf -- OUT
Impact: ... especially as he's essentially the last man standing at the position.
Fletcher Cox, DT, PHI: Neck -- OUT
Derek Barnett, DE, PHI: Calf -- OUT
Alex Smith, QB, WAS: Calf -- Active
Impact: Expected to start, especially with little other than Taylor Heinicke as an alternative.
Antonio Gibson, RB, WAS: Toe -- Active
Terry McLaurin, WR, WAS: Ankle -- Active
Impact: With a playoff spot on the line, he will give it a try. Don't expect 100%.
Kevin Pierre-Louis, LB, WAS: Ankle -- OUT
4:25 p.m. ET games
Chase Edmonds, RB, ARI: Hip -- Active
Impact: Once again, Kenyan Drake is the safer option in the Arizona backfield.
Larry Fitzgerald, WR, ARI: Groin -- Inactive
Impact: The veteran misses the finale, as does Christian Kirk, who is on the reserve/COVID-19 list.
Mike Davis, RB, CAR: Ankle -- OUT
Impact: Expect the Panthers to roll with an odd rotation of Rodney Smith ...
Christian McCaffrey, RB, CAR: Thigh -- OUT
Impact: ... Trenton Cannon, Alex Armah and Curtis Samuel in the backfield.
Cordarrelle Patterson, WR, CHI: Knee -- Active
Impact: Regardless, Darnell Mooney has been gaining momentum.
Cole Kmet, TE, CHI: Shoulder -- Active
Impact: Expect one more shining moment for Jimmy Graham, even with the rookie playing.
KJ Hamler, WR, DEN: Concussion -- OUT/IR
Impact: DaeSean Hamilton might get a slight value bump.
Duke Johnson, RB, HOU: Neck -- Inactive
Impact: Had been considered to be a 50-50 proposition as to whether he would play.
Michael Pittman Jr., WR, IND: Concussion -- Active
Impact: He'll be the Colts' No. 3 WR after clearing league protocol.
James Robinson, RB, JAX: Ankle -- OUT
Impact: Dare Ogunbowale will start for Jacksonville. Do you dare start him for your fantasy team?
DJ Chark Jr., WR, JAX: Shin -- OUT
Impact: Laviska Shenault Jr. and Keelan Cole Sr. expected to start.
Collin Johnson, WR, JAX: Hamstring -- OUT/IR
Impact: Chris Conley may also see an uptick in targets.
Patrick Mahomes, QB, KC: Team decision -- Inactive
Impact: No way you risk Mahomes' health in a meaningless Week 17 game.
Clyde Edwards-Helaire, RB, KC: Ankle -- OUT
Impact: With nothing on the line for the Chiefs, no need to rush back any injured players.
Le'Veon Bell, RB, KC: Knee -- Active
Impact: Even if Bell starts, he may not play more than token carries.
Sammy Watkins, WR, KC: Calf -- OUT
Impact: The No. 1 seed is locked up. Demarcus Robinson, Mecole Hardman ...
Tyreek Hill, WR, KC: Hamstring -- OUT
Impact: ... and Byron Pringle are likely to find themselves in the box score.
Jared Goff, QB, LAR: Thumb -- OUT
Impact: When John Wolford throws a pass in Week 17, it will be his first at the NFL level.
Cam Akers, RB, LAR: Ankle -- Active
Impact: The Rams need to win, and Darrell Henderson Jr.(ankle) is on the IR.
Cooper Kupp, WR, LAR: Illness -- OUT/IR
Impact: A positive COVID-19 test rules the receiver out for the finale.
Alvin Kamara, RB, NO: Illness -- OUT/IR
Impact: He's been placed on the reserve/COVID-19 list along with Latavius Murray. Taysom Hill/Ty Montgomery likely to get a ton of touches.
Carlos Hyde, RB, SEA: Illness -- OUT
Impact: Chris Carson leads the Seattle backfield, with Hyde not even making the trip.
Greg Olsen, TE, SEA: Foot -- Inactive
Impact: Will Dissly will start.
Deebo Samuel, WR, SF: Hamstring -- OUT
Impact: Expect to see the names Richie James and Kendrick Bourne ...
Brandon Aiyuk, WR, SF: Ankle -- OUT
Impact: ... and maybe even River Cracraft near the top of the box score.
Robbie Gould, K, SF: Illness -- OUT/IR
Impact: Tristan Vizcaino was signed from Minnesota as an emergency replacement.
Budda Baker, S, ARI: Neck -- Active
Brian Burns, DE, CAR: Shoulder -- Inactive
Troy Pride Jr., CB, CAR: Hip -- OUT/IR
Jaylon Johnson, CB, CHI: Shoulder -- OUT
Tashaun Gipson Sr., S, CHI: Neck -- Active
Bradley Chubb, LB, DEN: Ankle -- Inactive
Kingsley Keke, DE, GB: Concussion -- OUT
Phillip Gaines, CB, HOU: Knee -- Inactive
Rock Ya-Sin, CB, IND: Concussion -- OUT
Derrick Nnadi, DT, KC: Knee -- Active
Ben Niemann, LB, KC: Hamstring -- OUT
Joey Bosa, DE, LAC: Concussion -- OUT
Rayshawn Jenkins, S, LAC: Ankle -- OUT
Micah Kiser, LB, LAR: Knee -- OUT
Leonard Floyd, LB, LAR: Abdomen -- Active
Lamarcus Joyner, CB, LV: Thigh -- Active
Marcus Williams, S, NO: Ankle -- OUT
Javon Kinlaw, DT, SF: Knee -- OUT
Dre Greenlaw, LB, SF: Calf -- OUT
Richard Sherman, CB, SF: Calf -- OUT
Tarvarius Moore, CB, SF: Ankle -- Active
Daren Bates, LB, TEN: Hip -- Active
1 p.m. ET games
Julio Jones, WR, ATL: Hamstring -- OUT
Impact: Fantasy fliers to be found in the form of Brandon Powell and Laquon Treadwell?
Mark Ingram II, RB, BAL: Illness -- Active
Impact: He finally avoids being a healthy scratch this week, but how much will he actually play?
Gus Edwards, RB, BAL: Back -- Active
Impact: J.K. Dobbins could still get a healthy portion of the Ravens' carries.
Willie Snead IV, WR, BAL: Ankle -- Inactive
Impact: Marquise Brown likely to absorb some of Snead's targets.
Cole Beasley, WR, BUF: Knee -- OUT
Impact: John Brown activated from reserve/COVID-19 list to take his place.
Tyler Kroft, TE, BUF: Illness -- OUT/IR
Impact: Dawson Knox remains the Buffalo TE to roll with for fantasy.
Matthew Stafford, QB, DET: Ankle -- Active
Impact: Why wouldn't he play? Stafford has been fighting through these injuries for some time.
Kenny Golladay, WR, DET: Hip -- OUT
Impact: This should not be news for anyone, as the receiver has missed action since Week 9.
DeVante Parker, WR, MIA: Hamstring -- Active
Impact: Likely to play, at least for some of Week 17 ...
Jakeem Grant, WR, MIA: Ankle -- Inactive
Impact: ... however, Grant will not be able to suit up.
Dalvin Cook, RB, MIN: Personal -- OUT
Impact: A family emergency may place the ball into the hands of Alexander Mattison.
Dan Bailey, K, MIN: Back -- Active
Impact: The veteran had been optimistic about his chances of playing.
Damien Harris, RB, NE: Ankle -- OUT/IR
Impact: There's not much to see in the Patriots' backfield, though James White's value increases.
Nick Folk, K, NE: Back -- Active
Impact: Roberto Aguayo awaits oh so deeply in the wings.
Golden Tate, WR, NYG: Calf -- OUT
Impact: Dante Pettis might be in line for a few extra targets.
Ben Roethlisberger, QB, PIT: Team decision -- OUT
Impact: Pittsburgh plans to rest a ton of starters. Mason Rudolph will be the team's QB for Week 17.
Eric Ebron, TE, PIT: Illness -- OUT/IR
Impact: Vance McDonald steps in for the Steelers, who will be short-handed on offense.
Chris Boswell, K, PIT: Groin -- OUT
Impact: Matthew Wright once again steps into the role.
Darqueze Dennard, CB, ATL: Quad -- OUT
Calais Campbell, DE, BAL: Calf -- Active
Jimmy Smith, CB, BAL: Shoulder -- Inactive
Marcus Peters, CB, BAL: Calf -- Active
Marlon Humphrey, CB, BAL: Shoulder -- Active
Tre'Davious White, CB, BUF: Team decision -- Inactive
Mario Addison, DE, BUF: Team decision -- Inactive
William Jackson III, CB, CIN: Concussion -- OUT
Mackensie Alexander, CB, CIN: Illness -- OUT
Tae Davis, LB, CLE: Ankle -- Active
Leighton Vander Esch, LB, DAL: Ankle -- OUT
Xavier Woods, S, DAL: Ribs -- Active
Jamie Collins Sr., LB, DET: Neck -- Inactive
Ifeadi Odenigbo, DE, MIN: Chest -- OUT
Jalyn Holmes, DT, MIN: Groin -- OUT
Eric Kendricks, LB, MIN: Calf -- OUT
Cameron Dantzler, CB, MIN: Hamstring -- OUT
Lawrence Guy, DT, NE: Shoulder -- Active
Adam Butler, DT, NE: Shoulder -- Active
Byron Cowart, DT, NE: Back -- Active
Ja'Whaun Bentley, LB, NE: Shoulder -- Active
Anfernee Jennings, LB, NE: Shoulder -- Inactive
Devin McCourty, S, NE: Shoulder -- Active
Cam Brown, LB, NYG: Illness -- Active
Terrell Edmunds, S, PIT: Shoulder -- OUT
T.J. Watt, LB, PIT: Team decision -- Inactive
Joe Haden, CB, PIT: Illness -- OUT/IR
Carlton Davis, CB, TB: Groin -- Inactive