Who should you start? Who should you sit? To help you set your fantasy football lineups and to avoid starting a player who won't be playing, we'll post fantasy-relevant updates and analysis here as NFL teams release their official inactives lists, typically about 90 minutes before kickoff. Any rankings cited in this column come from our ESPN Fantasy staff ranks.
Official inactives should begin coming in approximately 90 minutes prior to the scheduled kickoff time.
Refresh often for the latest information.
Buffalo Bills at New Orleans Saints
Alvin Kamara, RB, NO: Knee -- OUT
Impact: The lack of practice in this short week was never a good sign.
Mark Ingram II, RB, NO: Knee -- INACTIVE
Impact: Tony Jones Jr. should get the bulk of the workload.
Adam Trautman, TE, NO: Knee -- OUT/IR
Impact: Nick Vannett to take over No. 1 TE duties for the Saints.
Marcus Davenport, DE, NO: Shoulder -- OUT
Zack Moss, RB, BUF: INACTIVE
Devin Singletary and Matt Breida will share the backfield touches against one of the toughest run defenses in the league.
Chicago Bears at Detroit Lions
Justin Fields, QB, CHI: Ribs -- OUT
Impact: Andy Dalton will start with Nick Foles as his backup.
Allen Robinson II, WR, CHI: Hamstring -- OUT
Marquise Goodwin, WR, CHI: Shoulder -- Active
Impact: Goodwin will start alongside Darnell Mooney.
Akiem Hicks, DT, CHI: Ankle -- OUT
Eddie Jackson, S, CHI: Hamstring -- Active
Tashaun Gipson Sr., S, CHI: Chest -- Active
Jared Goff, QB, DET: Oblique -- Active
Impact: Was a game-time call. Just leave him out of fantasy lineups and watch the parade in peace.
Jermar Jefferson, RB, DET: Ankle -- Active
Michael Brockers, DE, DET: Knee -- Active
Trey Flowers, LB, DET: Knee -- OUT
Las Vegas Raiders at Dallas Cowboys
Amari Cooper, WR, DAL: COVID-19 -- OUT
Impact: Michael Gallup and Cedrick Wilson get a chance to bask in the spotlight of a nationwide audience.
CeeDee Lamb, WR, DAL: Concussion -- OUT
Impact: Michael Gallup will assume the top receiver role while Cedrick Wilson will also see more targets.