The Presidents Cup and Ryder Cup partners opened with a tournament-record 59 on Thursday in best-ball play. They were at an event-record 17 under, with only one bogey through 36 holes.
Cantlay and Schauffele, starting on the back nine, birdied three of the first four holes to offset a bogey on the par-4 12th and added two birdies on their back nine.
"It was definitely more difficult playing alternate shot," Cantlay said. "I think 4 under is really good considering the circumstances with the wind and our round yesterday. I think it sets a really good tone going into the weekend."
Ryder and Redman, who belong to the same country club and share the same coach, followed their opening 61 with a bogey-free round. They birdied their opening two holes and added another on the fourth to make the turn. On the inward nine, they birdied the par-5 11th and the short par-4 13th before parring out.
"It's just been as stress free as it can in this kind of format," Ryder said. "You have a tendency, I think, sometimes to try harder because you're not just kind of feeling like you're letting yourself down, you're trying almost a little harder for your teammate. He's swinging it great, putting me in good positions off the tee, playing from the fairway, chipping it nice a couple times when we had to, and everything has just been solid."
Rai and Lipsky had six birdies, including four on their way to a 3-under par 33 on the front nine. They also opened with a 61.
"We played really well together," Rai said. "(Lipsky) hit some very good shots early on. I made a couple of putts and we kind of got the round going quite early.
The father-son team of Jay Haas and Bill Haas also made the cut on the number, following a 65 with a 71. At 68 years, four months, 20 days, Jay Haas, making his 799th official start, is the oldest player to make a PGA Tour cut.
Robert Garrigus and Tommy Gainey, each playing on sponsor exemptions, followed a first-round 61 with a 78 to miss the cut. Earlier in the week, Garrigus revealed he is applying for a release with the PGA Tour to play the inaugural LIV Golf competition.
The format shifts back to the best-ball Saturday. The final round will be alternate shot.