Marquette (9-3) took a 21-point halftime lead, and Presbyterian (2-11) never got closer than 18 the rest of the way. The Golden Eagles extended the lead to 30 points midway through the second half and took a 97-56 lead on David Cubillan's 3-pointer with 3:32 to go.
It was the fifth time this season that the Blue Hose have lost by at least 30 points and third time they lost by at least 40.
Marquette topped 100 points for the first time this season.
Senior Night: Celebrating NCAA athletes whose seasons were cut short amid coronavirus
The entire sports world was put on hold amid the coronavirus pandemic, leaving college seniors to ask, "What if?"
Homecoming: Jason Terry returns to Arizona as assistant coach
Arizona hired former Wildcats star Jason Terry as an assistant basketball coach Thursday.
Kentucky, Notre Dame to begin 3-year basketball series this fall
Kentucky and Notre Dame, who haven't played a regular-season game against each other since 2012, have signed a three-year deal in which each school will host a home game and the third will be played at a neutral site.