Payne, a 6-foot-9 senior, has missed the past six games because of a foot injury.
Under this new timetable, the seventh-ranked Spartans will be without Payne for Saturday's game at Madison Square Garden against Georgetown.
Michigan State has gone 5-1 without its second-leading scorer (16.2 points per game) and rebounder (7.7), after Tuesday night's 71-69 overtime win at No. 15 Iowa.
Information from ESPN.com's Andy Katz contributed to this report.