"A lot of hard work getting to this point, just getting to the big leagues," said Uggla, who came to the Marlins through the Rule 5 draft at the winter meetings and quickly became an All-Star. "I never take anything for granted."
The homer was Uggla's first in 53 at-bats.
"I exhaled," said Uggla, who got the ball back after the game. "I'm not going to lie."
Only four other second basemen in big league history have had three seasons of 30 homers or more: Rogers Hornsby (1922, 1925, 1929), Jeff Kent (1998, 2000, 2002), Alfonso Soriano (2002, 2003, 2005) and the Phillies' Chase Utley (2006, 2008, 2009).
Uggla has 151 home runs in five major league seasons, all with the Marlins. His career high is 32 homers, set in 2008.
Information from The Associated Press was used in this report.