Stanton hit his 155th home run in the Marlins' 7-5 loss to the New York Mets, tagging Dillon Gee for a long, two-run shot in the first inning. He began the day tied with Dan Uggla for the most homers in team history.
"I'll enjoy it later," Stanton said. Referring to Miami's mark this season, he added, "3-7 is the only record I know right now."
Stanton led the National League with 37 homers last year, with his last one coming Sept. 8. Three days later, he sustained multiple facial fractures when he was hit by a fastball from Milwaukee's Mike Fiers.
The 25-year-old Miami slugger is one of three active players in the majors to hold his team's franchise lead in home runs, along with Evan Longoria of the Tampa Bay Rays and Ryan Zimmerman of the Washington Nationals.
The Associated Press contributed to this report.