Segura initially took first base after he was examined by the training staff for several minutes. Before play resumed, he was replaced by pinch runner Hector Gomez.
Segura exited because he was feeling nauseated, manager Ron Roenicke said. He appeared to have avoided serious injury, although it was the second hit to the helmet he has suffered this season.
"He's doing pretty good, but we're going to get him over to a doctor here to make sure that they see the same things our guys are seeing," Roenicke said, according to the Milwaukee Journal Sentinel. "So we'll have him checked out here and then have a car for him to get back to Milwaukee tonight."
"I was just hoping it hit him in the head, not in the face, and that's actually what happened," Ramirez told the Journal Sentinel. "You never want to see that, even with the opposing team. You don't want to see anyone get hit in the head.
"That's dangerous out there."
"Yeah, that's two in the helmet. That's not a good thing," Roenicke told reporters. "You hope a guy doesn't get a little tentative in what he's doing. He does such a nice job doing the things we ask that you hope it doesn't start to bother him."
The Associated Press contributed to this report.