The ball was retrieved and authenticated by Major League Baseball with a QR code and a hologram. The league then put it up on its website for eight days before the auction closed after 84 bids at 11:18 p.m. ET Wednesday.
A Game 1-used third base, which was used for the first two innings only, was also sold Wednesday night for $6,260. Two game-used balls from the game sold for $900 and $1,220.
Other World Series game-used item auctions that will close in the next couple of days include Johnny Cueto's first-pitch ball in Game 2 and Noah Syndergaard's first-pitch ball for the New York Mets in Game 3, which buzzed Escobar's head and sent him to the ground.
Syndergaard's Game 3 jersey is also being auctioned off.
The highest price paid for a game-used ball purchased on Major League Baseball's website was the ball used to throw the first pitch of Game 7 of last year's World Series, which went for $28,890.
Last year, MLB.com also sold the ball used to make Derek Jeter's last out for more than $24,000.
Escobar's inside-the-park home run was the first in a World Series game since Mule Haas of the Philadelphia A's did it in 1929.