The arthroscopic procedure Monday was to repair some damaged meniscus cartilage in his left knee. There were no issues with the surgically repaired ACL in that knee.
Hamilton, 35, had left spring training in Arizona and returned to Houston for the second time in less than a week to be examined by Dr. Walt Lowe, who also performed Hamilton's season-ending surgery last June.
The latest knee procedure is the 11th in Hamilton's career, and the third since the slugger last played in the majors in 2015.
Hamilton, in camp on a minor league contract, faces six weeks of rehabilitation before he will be able to start running again.
Hamilton was a five-time All-Star as an outfielder. He has been working out this spring at first base to put less wear and tear on the knee.
He has not played in more than 90 big league games in a single season since 2013.
In 2010, he hit .359 with 30 home runs and 100 RBIs. In 2013, he hit 43 home runs with 128 RBIs.
Hamilton has a $24 million contract for 2017 and the Los Angeles Angels are obligated to pay the Rangers $22 million to cover most of it.
This is the final season of the $125 million, five-year deal he signed with the Angels as a free agent before the 2013 season, though they traded him back to Texas two years later.
The Associated Press contributed to this report.