Brewers manager Craig Counsell announced Tuesday that Burnes would start the Brewers' April 7 opener against the Chicago Cubs at Wrigley Field. The Cubs haven't yet named their starting pitcher.
Burnes, 27, has been one of baseball's best pitchers the past two seasons after struggling through a difficult 2019 campaign.
He went 1-5 with an 8.82 ERA in 2019 but followed that up by going 4-1 with a 2.11 ERA in the pandemic-delayed 2020 season. Last season, Burnes went 11-5 with an MLB-leading 2.43 ERA and struck out 234 while issuing only 34 walks in 167 innings.
This will be Burnes' first Opening Day start. Brandon Woodruff started the Brewers' season opener each of the past two years.