LeMahieu was scratched with left wrist discomfort and Stanton exited a 7-6, 11-inning win over Baltimore with right calf tightness. Major league-leading New York also placed closer Aroldis Chapman on the 15-day injured list Tuesday with left Achilles tendinitis and activated catcher Kyle Higashioka from the COVID-19 IL before ending a season-worst three-game skid.
LeMahieu was set to lead off and play third base against the Orioles, but New York announced he wouldn't play about 90 minutes before the first pitch. Manager Aaron Boone said LeMahieu had an MRI on Tuesday that came back clean. The three-time Gold Glove winner got a cortisone shot but is expected back within a day or two.
The Yankees are still waiting to learn more on Stanton, who will get an MRI on Wednesday. He was 0-for-2 with a strikeout as the designated hitter before exiting and being replaced by a pinch-hitter in the seventh inning.
LeMahieu, a two-time batting champion, is hitting .250 with three homers and a .704 OPS this season. He's 5-for-39 (.128) over his past 10 games. Boone said LeMahieu first had discomfort while pinch-hitting Monday, then felt it again during batting practice Tuesday.
"Really good news,'' Boone said of the diagnosis. "We're pretty optimistic that hopefully he's back, if not tomorrow, the next day probably.''
Stanton is batting .285 with 11 homers and a team-leading 35 RBIs. The 2017 NL MVP played 139 games last year after injuries and the pandemic limited him to 41 games in 2019 and 2020 combined.
"Not sure if it's the calf, if it's part of the calf, or what,'' Boone said. "We'll know more in the morning.''
Chapman had an MRI on Monday that came back negative for a tear. Boone said Tuesday that Chapman was improving but not game ready.
Donaldson was sidelined by the virus Monday, shortly before being suspended one game by Major League Baseball for taunting Chicago White Sox shortstop Tim Anderson with multiple references to Jackie Robinson over the weekend.