Senzatela was hurt during his start Thursday at St. Louis. He and first baseman Elehuris Montero were both racing toward Brendan Donovan's second-inning grounder when Senzatela broke toward first base in a sudden change of direction. His knee buckled and he fell to the ground, holding his leg in his hands and clearly in pain.
"It's a tough one for Antonio," Black said before the Rockies hosted San Francisco on Friday night. "I feel bad for him. The season comes to an end due to injury, and a lengthy one. But he'll get the repair and he'll be back, hopefully in six to eight months."
Senzatela, who's in the first season of a five-year, $50 million contract, went 3-7 with a 5.07 ERA in 19 starts this season. He is 39-42 with a 4.88 ERA in six seasons, all with Colorado.
He's expected to have surgery sometime in the next two weeks.
The Rockies placed Senzatela on the 15-day injured list and reinstated pitcher Jhoulys Chacin.