Foreign nationals who aren't vaccinated against COVID-19 aren't allowed to enter Canada, save for limited exceptions that require a 14-day quarantine. Unvaccinated baseball players are placed on the restricted list, where they are not paid and do not accrue major league service time.
Loup will lose $123,626, Tepera $115,385 and Ward $11,868.
Hitting coach Jeremy Reed also did not accompany the team to Toronto for the three-game series.
"We knew coming in who we were and weren't going to have here," Angels interim manager Phil Nevin said. "I just look at it as an opportunity to see some guys maybe we wouldn't have."
The slumping Angels have lost six straight and nine of 10. Los Angeles is 0-4 against Toronto this season.
On Monday, the Chicago Cubs become the final new team to play in Toronto this season. Only Toronto's four AL East opponents are scheduled to visit Canada in September. So far, 43 players have been placed on the restricted list for games against the Blue Jays, with Boston pitcher Tanner Houck missing two series in Toronto.
Kansas City had 10 players absent for a series before the All-Star game, including Whit Merrifield, who later got vaccinated and was traded to Toronto at the deadline.
The Yankees, Rangers and Astros all brought full vaccinated rosters to Toronto. So did Baltimore on its most recent trip earlier in August.
Aguilar hit .280 with 15 homers and 48 RBI in 88 games at Rocket City. He was in the lineup in right field Friday, batting ninth. Nevin said Aguilar could play all three games against Toronto with Ward absent.
Ward is batting .261 with 17 homers and 46 RBI in 101 games.
Tepera and Loup are both former Blue Jays. Tepera is 2-2 with a 3.80 ERA and two saves in seven chances, while Loup is 0-4 with a 4.51 ERA in 51 games.