White told ESPN on Tuesday the 205-pound contest will headline a UFC Fight Night on Feb. 27. The UFC has not yet announced an official venue for any of its events in 2021.
Reyes (12-2) nearly won the light heavyweight title twice this year. He came up just short in a decision loss to then-champion Jon Jones at UFC 247 in February in a five-round bout many felt Reyes won. Reyes, an American fighter, was granted another title shot after Jones vacated the belt this summer but suffered a TKO loss Jan Blachowicz.
Prochazka (27-3-1), a native of the Czech Republic, made a spectacular UFC debut in July on Yas Island in Abu Dhabi, United Arab Emirates, knocking out former title challenger Volkan Oezdemir in the second round at UFC 251. It was the 24th win by knockout in Prochazka's professional career.