The main card at the Moody Center is on ESPN and ESPN+ at 7 p.m. ET, following prelims on ESPN+ at 4 p.m.
Dariush (22-5-1) is coming off a June loss to former champion Charles Oliveira, which ended an eight-fight winning streak. Dariush is No. 4 in the ESPN lightweight rankings.
The eighth-ranked Tsarukyan (20-3) has won two in a row and seven of his last eight. His most recent win was a third-round TKO of Joaquim Silva in June.
How to watch the fights
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Saturday's UFC fight card
ESPN/ESPN+, 7 p.m. ET
Lightweight: Beneil Dariush vs. Arman Tsarukyan
Lightweight: Jalin Turner vs. Bobby Green
Men's bantamweight: Rob Font vs. Deiveson Figueiredo
Welterweight: Sean Brady vs. Kelvin Gastelum
Lightweight: Clay Guida vs. Joaquim Silva
Middleweight: Punahele Soriano vs. Dustin Stoltzfus
ESPN+, 4 p.m. ET
Women's bantamweight: Miesha Tate vs. Julia Avila
Middleweight: Zachary Reese vs. Cody Brundage
Lightweight: Drakkar Klose vs. Joe Solecki
Men's featherweight: Steve Garcia vs. Melquizael Costa
Light heavyweight: Rodolfo Bellato vs. Ihor Potieria
Welterweight: Wellington Turman vs. Jared Gooden
Women's flyweight: Veronica Hardy vs. Jamey-Lyn Horth
Reed Kuhn's betting tip
It's a grappler's delight for the main event. On paper, these two are eerily similar in a number of important ground metrics. But Tsarukyan's youth and durability could give him the upper hand on the feet round over round against Dariush, who is pushing 35 years old with five prior knockdowns.
For Kuhn's suggested bets on the main event and other fights on Saturday's card, check out the ESPN+ expert picks and best bets article when it publishes Thursday. It also features analysis by Xtreme Couture MMA coach Eric Nicksick as well as ESPN's other betting expert, Ian Parker.