He was averaging 5.3 points and 2.7 rebounds per game this season. While he wasn't expected to see major playing time, a right calf strain for Omer Asik put him in the lineup.
The Pelicans, who also are missing Norris Cole (left ankle sprain), guard Tyreke Evans (right knee) and forward Quincy Pondexter (left knee), have lost five straight after a 121-115 defeat to the Atlanta Hawks on Friday night.
The Pelicans have said there is no timetable for how long Perkins will need to recover. Cole and Evans also don't have timetables for their returns.
''It's going pretty good just rehabbing, trying to get the strength back,'' Evans said, according to NOLA.com. ''That's pretty much it. I started running, which is a good sign. Just trying to get used to get back in the flow and working my way back up. Once I feel I can stop on the dime and be me, that when I'll be ready. I'm running on the treadmill and trying to strength it up.''
The Associated Press contributed to this report.