Jokic sat out a game last week to rest a sore right wrist. He also missed three games in November because of the NBA's health and safety protocols.
The two-time reigning NBA MVP has triple-doubles in five of his past six games. He's averaging 25.1 points, 11 rebounds and 9.9 assists this season.
Jamal Murray picked up the slack Friday, logging the first triple-double of his career with 17 points, 14 assists and 10 rebounds.
"He steals a lot of my triple-doubles,'' Murray said jokingly. "It was nice to finally get one on the board.''
The Nuggets are 3-2 without Jokic in the lineup this season.
"It was really fun to see our guys continue to play the way we play regardless of who's on the court,'' Nuggets assistant coach David Adelman said. "It was fun because a lot of guys contributed. Those are special nights.''
Adelman was serving as the acting head coach for a third straight game, all wins. Head coach Michael Malone remained out after entering the league's health and safety protocols.
Forward Vlatko Cancar also sat out Friday's game because of an illness not related to COVID-19. Forward Jeff Green was available after missing 14 games because of a fractured hand and played 18 minutes.
The Associated Press contributed to this story.