"I think we just lost (Ginobili) again, and (Splitter)," Spurs coach Gregg Popovich said following the game, which the Spurs won 103-100. "I think it's going to be a while."
Ginobili left at the end of the third quarter with a strained left oblique. Splitter came out of the game in the first quarter with a right calf sprain. Both will be examined in Los Angeles on Saturday, according to a team official.
"It sort of looks like we won the battle, but it makes it tough to win the war," Popovich said.
Saturday was Ginobili's fourth game back since being sidelined for 22 games after he broke his left hand in a game against Minnesota on Jan. 2. Ginobili was wincing in pain after Clippers forward Kenyon Martin set a hard screen on him away from the ball. Ginobili came out of the game moments later.
Entering Saturday's game, Ginobili, a two-time All-Star, had played only eight games for the Spurs, averaging 13.4 points on 56.3 percent shooting from the field.
Splitter has served as a key reserve in the frontcourt for San Antonio in his second season with the Spurs. Prior to Saturday's game, he'd tallied 9.7 points per game while shooting 62.3 percent from the field to go along with 5.4 rebounds in 21.3 minutes.
Kevin Arnovitz covers the NBA for ESPN.com.