Wade's wrist is the latest issue as injuries become as big a concern for the Heat as their recent stretch of losses.
Chris Bosh's return to action remains uncertain as he continues to work his way back from a sprained left ankle that has kept him out of the past four games. Both Wade and Bosh traveled with the team Saturday afternoon to Oklahoma City for Sunday's 1 p.m. nationally televised game.
The Heat's injuries extend beyond Bosh and Wade, with LeBron James (ankle), Mike Miller (knee, thumb) and Eddie House (ankle) either aggravating lingering aches or emerging from Friday's escape against the Pistons with set of new painful concerns.
James tweaked his left ankle in the second half against the Pistons and banged the back of his head on a fall. But he remained in the game and finished with 39 points, nine assists and eight rebounds in 44 minutes. Miller, who has played through soreness in his surgically repaired right thumb, bruised a knee and twisted an ankle during the game. He played most of the second half with a profound limp.
With Bosh and Wade already out, and forward Udonis Haslem still expected to miss another couple of months after foot surgery, the Heat had few other options to finish out Friday's game. But with key players hurting, the Heat (32-14) have lost five of their last seven games heading into Sunday.
Those struggles began when James turned his left ankle in the fourth quarter of the Heat's Jan. 12 road loss to the Los Angeles Clippers. It was also the last game James, Bosh and Wade played together. Since the, James and Wade have missed two games while Bosh has sat out four.
Michael Wallace covers the Miami Heat for ESPN.com.