Ferguson's injury creates big void in Big D

The Dallas Cowboys got off to a good start with their 45-35 victory over the New York Giants. The 45 speaks for itself, but the 35 will need to be addressed quickly.

Based on what I saw and who was playing, the Cowboys need to get CB Terence Newman back on the field as soon as possible. They also need one of their backup cornerbacks to emerge as a quality No. 3 option. The sooner players such as CBs Jacques Reeves and Nate Jones are able to function effectively behind the starters, the better the Cowboys' defense will be.

Also, the season-ending injury to DT Jason Ferguson is going to be an issue. He is the most experienced inside defensive lineman on the team. His absence will definitely hurt Dallas.

Looking ahead to Week 2, these three games stand out to me.

San Diego at New England:
This will be an interesting game, to say the least. I think the Chargers' only chance will be to pressure QB Tom Brady and try to play a deliberate game by keeping the ball from New England. They can do a certain amount of that with RB LaDainian Tomlinson, obviously. To beat New England, the Chargers will definitely have to score more than they did in Week 1 (a 14-3 victory over the Bears). Tomlinson didn't really get going against the Bears (just 25 yards on 17 carries), but he was there when the Chargers needed him. This is undoubtedly a big game for a lot of reasons. These two teams, along with the Ravens, are viewed as the AFC's best. There is a little bit of territorial dominance and pecking-order stuff going on. Even though it's only Week 2, this game could also have an effect on home-field advantage in the playoffs. And don't forget that New England ended the Chargers' 2006 season. Make no mistake, players take that stuff seriously and personally. There will be an edge to the game, no doubt.

Indianapolis at Tennessee:
The Titans know how to play the Colts tough. Last season, Tennessee lost 14-13 at Indy and beat the Colts 20-17 at home. The Titans' defense looks to be improved based on its Week 1 performance against Jacksonville (a 13-10 Tennessee win). Titans coach Jeff Fisher has faced the Indy offense run by coach Tony Dungy and offensive coordinator Tom Moore for a long time now. I think the Titans have a good idea about how to approach Indianapolis based on the two games from last year. I'm sure they will try to control the game with RBs Chris Brown and LenDale White, as they did against the Jaguars. The Titans again will try to keep it close and win it at the end.

New York Jets at Baltimore:
Assuming that QB Chad Pennington is out, this is a very tough game for the Jets. The Ravens' defense is a tough task for any quarterback, especially one as inexperienced as second-year player backup Kellen Clemens. He could not be facing a team that gives a quarterback more problems. Clemens will be challenged on every play to identify the personnel correctly, to call the right protections and to recognize the different types of pressure the Ravens use. The Ravens' various blitzes and schemes are very tough for a young QB to figure out. I think he'll have a hard time because the Ravens will be coming after him.

Bill Parcells, the former head coach of the Giants, Patriots, Jets and Cowboys, is a regular contributor to ESPN.com.