Wilson has started eight games for the Texans this season and has 29 tackles, a forced fumble and two interceptions. He will be replaced in the lineup by John Busing.
The Texans signed veteran safety Brian Russell, recently released by the Jaguars, to fill Wilson's spot on the roster.
In other injury news, linebacker DeMeco Ryans (ankle) and running back Steve Slaton (shoulder) both missed practice Wednesday with minor injuries. Coach Gary Kubiak said they are listed as day to day for Sunday's game against the Colts.