News: 16 hours agoGaroppolo (calf) will start Sunday's game against the Colts, Nick Wagoner of ESPN.com reports.
Spin: Trey Lance (ankle) is ruled out on the Friday injury report, while Garoppolo has no designation for the game. The veteran QB will suit up for the first time since Week 4, with Nate Sudefeld coming up from the practice squad to provide depth. Garoppolo returns to face the Colts, who have struggled against the pass this year with a 15:5 TD:INT and 7.4 net yards allowed per attempt (sixth worst).
ESPN Fantasy Projection: Following yet another injury-plagued season, Garoppolo is no longer the quarterback of the future in San Francisco. The 49ers drafted Trey Lance with the third overall pick in April, which means it's only a matter of time until the 29-year-old incumbent is sent to the bench. Even if Garoppolo is under center to open 2021 (which is the expectation), there isn't much weekly fantasy appeal here. Back in 2019, Garoppolo appeared in all 16 regular season games for the first time in his career and ranked top-5 in pass TDs (27), completion rate (69%) and YPA (8.4). However, low pass volume (19th in attempts) and minimal rushing contributions allowed him a career-high 14th place finish in fantasy points. Garoppolo should only be drafted in two-QB leagues.