"Hell, no," Tulloch told the Free Press at an event to benefit his Stephen Tulloch Foundation Friday night. "I'd do it again, brother. You do it every time. If it's going to happen, it's going to happen. Just a matter of time."
Tulloch will have surgery next week. He hadn't missed a game since being drafted in the fourth round in 2006 by the Titans out of NC State. He played in 131 straight regular-season games between Tennessee and Detroit, where he has spent the past four seasons.
Tulloch said he wasn't in any pain.
"That's what's crazy," Tulloch told the Free Press. "No swelling. Even the trainers are like, 'Man, how are you walking?' I don't have any pain. Nothing."
ESPN.com's Michael Rothstein contributed to this report.