The Cleveland Browns tight end was ruled out for the game because of a concussion. Cameron was injured during the team's win against Oakland.
The situation at least raises the question of whether Cameron will be back for the road game against Cincinnati on Thursday night, four days after the Bucs game.
"That's always a concern when you have fewer days, sure," coach Mike Pettine said.
It's the third time in just more than two years that Cameron has missed time with a concussion, and the second time this season he's missed a game due to injury. He also did not play against New Orleans earlier this season, a game the Browns won with a last-minute field goal.
"There are certain things that Jordan can do that he's special at," offensive coordinator Kyle Shanahan said. "I think Jordan has a lot of talent, especially stretching the field, but I do feel very good about Barnidge and Dray stepping in. They're both good run blockers and they both can help us in the pass game.
"You don't feature them as much [as] you would a Pro Bowl tight end, but as far as going vs. zones and stuff and even some man-to-man situations, I think we'll be all right."
Cameron was injured at the end of a diving catch. As he was extended to make the play, Raiders safety Brandian Ross hit him in the neck and head area, causing Cameron's neck to snap forward in a scary way. The league fined Ross $22,050 for the hit on Friday, ruling it was on a defenseless receiver. Ross makes $469,412 this season, or $27,612 per week.