The Atlanta Police Department's public affairs office issued a statement confirming the accusation.
"The Atlanta Police Dept. has been contacted by a female who advised she was sexually assaulted by Sammie Hill, who is a NFL player. We are working with the female to obtain information about this incident. At this time, the report is not available," the statement said.
Titans coach Ken Whisenhunt said at his Monday afternoon news conference the team was aware of the allegation and would soon issue a statement.
A bit later the team said: "We are aware of the TMZ report. We will let the police investigate the allegation and we will provide any assistance they need. We have discussed the matter with Sammie and we will continue to gather facts."
Hill's agent, Brian Levy, did not respond to an email seeking comment.
Hill has played in all 13 games for the Titans this season. Defensive coordinator Ray Horton offered Hill a rave review last week.
"He wins at his position probably at an 85 percent clip," Horton said. "If he's on a more talented team and getting more sacks, he'd be mentioned as a potential team MVP and, on the right team, a potential Pro Bowl nose guard."
Hill has 25 tackles and two sacks on the season.