When Jameis Winston and Marcus Mariota take the field at Raymond James Stadium, it will mark the first time quarterbacks selected with the first two picks in the draft have opposed each other in their NFL debuts. It's not the first time these two have locked horns, however, as Mariota and Oregon romped past Winston and Florida State in the 2015 Rose Bowl.
So the past two Heisman Trophy winners renew their acquaintance Sunday, but now each carries the expectation of becoming a franchise savior.
With that in mind, ESPN.com recalls 10 of the most eagerly anticipated matchups between young stars:
John Elway vs. Dan Marino
Sept. 29, 1985: If Elway had been willing to play for the Colts, who drafted him No. 1 overall, this matchup would have been an AFC East staple twice annually. Instead, he maneuvered his way to the Denver Broncos, postponing his battle with Marino and the Miami Dolphins by two years. Marino, the reigning NFL MVP, outperformed Elway in Mile High Stadium by leading Miami to a 30-26 victory. The Dolphins quarterback completed 25 of 43 passes for 390 yards, three touchdowns and no interceptions. On the other side of the ledger, Elway was 18-of-37 for 250 yards, no touchdowns and an interception. Marino went on to lead Miami to the playoffs 10 times but never won a Super Bowl. Elway made five Super Bowl appearances, winning twice.
Nov. 5, 2003: More than 300 media credentials were issued for this clash of future superstars, which also served as the first home game in James' pro career. James, the No. 1 pick in the 2003 NBA draft, had seven points, 11 rebounds and seven assists in 41 minutes for the Cleveland Cavaliers. Anthony, the No. 3 selection, put up 14 points, six rebounds and two assists for the Denver Nuggets. The Ohio native who shined brightest on this night wasn't James, though. It was Nuggets guard Earl Boykins, a former Cavalier, who came off the bench to score 18 second-half points as Denver hung on for a 93-89 victory. James would go on to be named Rookie of the Year, but it was No. 2 pick Darko Milicic who would win a championship that season -- scoring one point in 14 postseason minutes with the Detroit Pistons.
Nov. 24, 1984: Believing their biggest need was at the center position, the Portland Trail Blazers memorably selected the talented but injury-prone Bowie with the No. 2 pick in the 1984 NBA draft, allowing the Chicago Bulls to grab Jordan at No. 3. The teams met on Nov. 24, 1984, at Portland's Memorial Coliseum, where the hosts maintained a long sellout streak that would remain intact for another decade. Jordan scored 30 points as the main offensive weapon for the Bulls, while Bowie scored 11 off the bench for the Blazers, who won 141-131. Jim Paxson and Clyde Drexler -- two reasons that Portland opted to draft a center instead of a guard -- combined for 50 points for the Blazers. Less than a month later, Jordan and the Bulls played host to No. 1 overall pick Hakeem Olajuwon and the Houston Rockets. Olajuwon outscored Jordan 24-18, and the Rockets won 104-96.
Peyton Manning vs. Ryan Leaf
Oct. 4, 1998: The top two picks in that year's draft faced off in Week 5, with Manning and the Colts scratching out a 17-12 win over the visiting Chargers. Both quarterbacks had pedestrian efforts statistically. Manning completed 12 of 23 passes for 137 yards, one touchdown and one interception. Leaf was also 12-of-23, with 160 yards, no touchdowns and an interception. It was the first victory of Manning's NFL career. It was the third consecutive loss for Leaf after starting the season 2-0, and he would win just two more games in his career as a starter.
Magic Johnson vs. Larry Bird
Dec. 28, 1979: Nine months after their memorable clash in the NCAA Tournament championship game, the budding superstars met for the first time as professionals. The anticipation was palpable, and the Los Angeles Lakers enjoyed their first home sellout in nearly two years. Johnson, just 20 years old, had 23 points, eight rebounds and six assists -- albeit with seven turnovers -- as the Lakers coasted to a 123-105 win over the Boston Celtics. Bird, who was 23, countered with 16 points, four rebounds and three assists. Bird went on to win rookie of the year honors, but Johnson and the Lakers won the NBA championship that season. Johnson and Bird clashed 37 times as pros, and Johnson's Lakers won 22 of those games, including two of three NBA Finals series.
Kevin Durant vs. Greg Oden
Feb. 6, 2009: Fans had to wait a year for this showdown, as Oden missed the 2007-08 season recovering from microfracture surgery on his right knee. Durant stole the spotlight by leading the Oklahoma City Thunder, playing in their first season after relocating from Seattle, to a 102-93 victory over the Trail Blazers in a game that wasn't as close as the score might indicate. The reigning rookie of the year racked up 31 points, three rebounds and two assists in 43 minutes. Oden had four points, two rebounds and two assists in 16 minutes. Durant went on to win four scoring titles and the 2014 MVP award. Oden played in only 105 career games while battling injuries.
Dwight Gooden vs. Roger Clemens
Oct. 19, 1986: Two young fireball-throwing rock stars took the mound at Shea Stadium in Game 2 of the 1986 World Series for what it seemed would be a pitching matchup for the ages. As it turned out, neither player was at his best as the Boston Red Sox won 9-3 to take a 2-0 series lead over the New York Mets. Clemens went 4⅓ innings, allowing five hits, four walks and three runs. Gooden struck out six in five innings, but suffered the loss by giving up eight hits and six runs. Boston reliever Steve Crawford earned the win. Gooden also took the loss in Game 5, allowing four runs and nine hits in four innings. Clemens pitched seven strong innings in Game 6, but Boston lost on Bill Buckner's infamous 10th-inning error. The Mets capped one of the most memorable World Series in history with an 8-5 win in Game 7.
Jan. 21, 1998: At the 1998 Australian Open, Venus was 17 and already playing in her fourth major. Serena was 16 and playing in her first. They met in the second round, with Venus winning 7-6, 6-1. Venus then won her next two matches before losing to Lindsay Davenport in the quarterfinals. What followed is now part of tennis lore. Serena is currently No. 1 in the world with 21 major titles to her credit. Venus has won seven majors -- more than any active WTA player not related to her. Venus won the first three matchups against Serena, but the younger sister now holds a 16-11 advantage after winning earlier this week at the U.S. Open.
Nov. 22, 2005: It was standing-room only at the Igloo in Pittsburgh as two of the most hyped rookies in NHL history met up for the first time as pros. A year earlier, Crosby had helped Canada win the gold medal at the World Junior Championships against Ovechkin and Russia. In this matchup, Crosby had a goal and an assist to lead the Pittsburgh Penguins to a 5-4 win over the Washington Capitals. Ovechkin had scored 15 goals in his first 20 games, but he tallied only an assist against the Pens. Ovechkin won the Calder Trophy as NHL rookie of the year and is a three-time winner of the Hart Trophy, given to the league MVP. Crosby has twice earned the Hart and won the Stanley Cup in 2009.
Aug. 28, 2000: The stage was set for this duel when Woods outlasted the rookie pro Garcia by one stroke in the 1999 PGA Championship at Medinah. It was the second major championship for Woods and a coming-out party for the emotional, energetic Garcia. Observers predicted the duo would embark on a long, high-voltage rivalry. At an exhibition in Palm Desert, California, dubbed the Battle at Bighorn, Woods and Garcia went head-to-head for a $1.1 million payday. Garcia edged Woods, who had the flu and had traveled from Ohio earlier in the day, 1-up to win the made-for-TV event. It was hardly an indicator of things to come, however. Woods has won 14 majors in his career, while Garcia is still seeking his first.