Stafford did, on the first drive of the second half, and he was replaced by backup Dan Orlovsky, part of a 42-17 Arizona Cardinals victory over the winless Lions. However, Lions coach Jim Caldwell said Stafford will remain the team's starting quarterback.
"Really, it's like a pitcher not having a very good day," Caldwell said. "The pitcher comes out, and the pitcher, obviously, he's still the starter. He's still our starter. There will be no issues there, so there is no quarterback controversy or anything of that nature.
"But I know one thing. We've got to get better. This was poor, just not the kind of outing that we'd like to see around here."
Stafford completed 20 of 32 passes for 188 yards, a touchdown and three interceptions before being replaced. Orlovsky, playing his first game with the Lions since the winless 2008 season, completed 21 of 38 passes for 191 yards, a touchdown and an interception.
Caldwell said the Lions "weren't getting anything done consistently on offense," so he was trying to "change the direction" at that point, even though the Lions were trailing 35-7 by the time Orlovsky entered the game.
"We just didn't play well," Stafford said. "It starts with me. I got to play better. Turn the ball over in the first half, defense did a good job the first couple times trying to get it back for us, did a good job of that.
"But continue to make mistakes and turn the ball over, and you can't do that and try to win games."
Orlovsky said nothing surprises him, including going in midway through the third quarter with the Lions struggling.
The Lions are now No. 31 in the NFL at 292.8 yards per game and continue to have the league's worst run offense. Caldwell said despite Detroit's continued offensive struggles, there will be no coaching changes this week. He said it is his fault the Lions had "no spark, no explosiveness, no nothing" against Arizona on Sunday.