Romo remains on the injured reserve/designated to return list and can't play until Nov. 22 against the Miami Dolphins, but Wednesday is the first day he was eligible to return to practice under league rules.
He took part in pat-and-go in warm-ups, worked through some individual drills and threw passes during the routes-on-air portion of practice.
While the remaining quarterbacks worked on handoffs with the running backs, Romo, who was in shoulder pads, worked through some throwing on the move with offensive coordinator Scott Linehan.
Romo threw a variety of routes to Terrance Williams, Cole Beasley, Vince Mayle, Devin Street and Jason Witten during the portion of practice that was open to the media and did not have an incompletion.
Matt Cassel will take all of the first-team snaps as the Cowboys get ready to play the Philadelphia Eagles this week, but Romo could see some work in team drills next week. As the Cowboys work through team drills Wednesday, Romo is expected to throw more on the side, according to coach Jason Garrett.
"One of the things about Tony is in his absence he always stays engaged," Garrett said. "It's not like he has been away. But it will be nice to see him out there throwing a little bit. He was throwing a little bit last week. That's always a positive sign.
"He has a great way about him. He is a natural leader. He has been really helpful during the week of preparation and also during the game for the other quarterbacks and whole football team."