The Patriots' injury report released after practice Friday officially listed Brady as questionable with illness. Gronkowski, whose absence was not injury related, was listed as probable.
"It's always strange when he's not out there," special-teams captain Matthew Slater said of Brady. "It's come up a time or two. It was a good day for Jimmy [Garoppolo] to get some work and for us to continue to get better. Obviously, we're optimistic that 12 will be out there Sunday ... We're counting on him being there."
New England will clinch a first-round bye with a win and a Denver loss. The Patriots have won five in a row against Tennessee.
Information from The Associated Press was used in this report.