The NCAA has denied the final appeal for a medical hardship waiver of defensive end Drew Ott, who was seeking a fifth season of eligibility at Iowa.
Ott will enter the NFL draft.
A second-team All-Big Ten selection in 2014, Ott suffered a torn ACL in Week 6 last season. He missed the Hawkeyes' final eight games and was also limited in the first month of the season after dislocating an elbow in Week 2.
Iowa sought a ruling from the Big Ten, which forwarded the decision in March to the NCAA. Ott's case was denied. He appealed in advance of the final ruling this week.
Ott was allowed to attend the NFL combine in February while awaiting word on his eligibility. He did not work out as he continued to rehab from the October knee surgery.
Iowa coach Kirk Ferentz expressed frustration last week with the administrative delay in reaching a decision on Ott.
"Drew's got a life to live, too," Ferentz said before the verdict. "And this is a big month for him if the ruling doesn't go his way. It's been a long time. They need to let him know what the situation is. I wish it could move a little quicker. I think we all do."
A former 8-man high school player from Trumbull, Nebraska, Ott closes his Iowa career with 15 1/2 sacks and 26 tackles for loss.