Hyde suffered the injury when he was hit in the left leg on a carry. Hyde walked off the field under his own power but did not return.
"It didn't feel that bad when it first happened. It's pain, there's some pain, but it didn't feel like bad pain. I've felt worse," Hyde said after Saturday's win. "That's why I was able to get up and walk off on my own."
Hyde finishes the season with career highs of 988 yards rushing and six touchdowns.
Information from ESPN San Francisco 49ers reporter Nick Wagoner contributed to this report.