"I poured my heart and soul into this season so it's unfortunate," Ryan wrote in a message posted on his Twitter page. "However, anyone who knows me knows how relentlessly I will train to come back a better player with fewer weaknesses."
Titans coach Mike Vrabel said Monday that he hadn't decided who will replace Ryan in the lineup.
"Whoever plays in there is going to be expected to do a good job," he told reporters.
Ryan wasn't the only key member of the Titans' secondary injured Sunday. Safety Kenny Vaccaro suffered a concussion and is currently in the protocol, Vrabel said Monday.