James was diagnosed with a stress fracture of the fifth metatarsal of his right foot, according to the team, and will continue to be evaluated. The Chargers have not determined a course of treatment.
He was seen with a walking boot on his right foot at his team's second joint practice with the New Orleans Saints on Friday.
😔 no no no no no DJ https://t.co/6wDLUTs4zX— F L ⚡️ S H (@Melvingordon25) August 16, 2019
James had not missed a training camp practice and played 11 snaps in the Chargers' opening preseason game last week against the Arizona Cardinals.
The Florida State product played in all 16 games last season. He led the Chargers in tackles (105) while posting 3.5 sacks, 3 interceptions and 15 pass breakups, earning All-Pro and Pro Bowl honors as a rookie.
Fellow Pro Bowler Adrian Phillips worked with the starters at strong safety with James unavailable.