Source: Arizona Cardinals not optimistic QB Kyler Murray, WR DeAndre Hopkins play vs. Panthers

The Arizona Cardinals are not optimistic that quarterback Kyler Murray will play Sunday against the Carolina Panthers at State Farm Stadium, but have yet to make a decision, a source told ESPN's Adam Schefter on Saturday.

Star wideout DeAndre Hopkins, listed as questionable with a hamstring injury, is also unlikely to play, the source said.

Murray sprained his left ankle in the fourth quarter of a loss to the Green Bay Packers on Oct. 28. He was inactive for last Sunday's win over the San Francisco 49ers after being listed as a game-time decision.

Hopkins also missed Sunday's game after injuring his hamstring against the Packers.