Seattle Seahawks running backs Kenneth Walker (ankle) and DeeJay Dallas (ankle) will not play against the Carolina Panthers on Sunday.
Both had been listed as questionable but did not practice this week because of their injuries.
Seattle will have to lean on a trio of running backs: Tony Jones Jr., Travis Homer and Godwin Igwebuike. The Seahawks elevated Igwebuike from the practice squad Saturday.
Jones and Homer have combined for just 16 carries for 57 yards this season, while Igwebuike has yet to record a carry.
Seahawks receiver DK Metcalf will play despite being listed as questionable with a hip injury. The Seahawks will monitor his workload closely to make sure he is feeling good coming off the injury, a source told ESPN's Jeremy Fowler on Saturday.