Prior to the injury, Muzzin scored a goal in the first period to extend his scoring streak to six games. He has six goals and 17 assists in 53 games this season.
On Monday, the Maple Leafs signed Muzzin to a four-year contract extension with an average annual value of $5.625 million. If Muzzin misses four weeks, he will return with six games remaining in the regular season.
Toronto is in third place in the Atlantic Division, two points ahead of the Florida Panthers. The two teams face off Thursday night in Sunrise, Florida.
Information from The Associated Press was used in this report.