Cristiano Ronaldo announced on social media on Monday that one of his newborn twins has died.
"It is with our deepest sadness we have to announce that our baby boy has passed away," the Manchester United striker wrote in a post also signed by his partner, Georgina Rodriguez.
"It is the greatest pain that any parents can feel."
Manchester United confirmed that Ronaldo would not travel to Anfield to face Liverpool on Tuesday evening. A statement read: "Family is more important than everything and Ronaldo is supporting his loved ones at this immensely difficult time."
Ronaldo announced last year that the couple was expecting twins.
"Only the birth of our baby girl gives us the strength to live this moment with some hope and happiness," he wrote on the social media post.
"We are all devastated at this loss," the post added, "and we kindly ask for privacy at this very difficult time. Our baby boy, you are our angel. We will always love you."
Ronaldo has four older children.