The Premier League champions eased past Lincoln City 7-2 in the third round on Thursday, while Aston Villa and Manchester City also won their ties to advance to fourth round matches against Stoke City and Burnley, respectively.
Arsenal and Liverpool will meet at Anfield in the Premier League on Monday evening and will then line-up on Merseyside again later in the week, most likely on Thursday. It will be the third time they have met in little over four weeks, with Arsenal winning the Community Shield on penalties following a 1-1 draw.
Chelsea will host Tottenham Hotspur, after Leyton Orient were forced to forfeit their third-round tie against Spurs when the League Two club returned several positive coronavirus tests. However, Spurs will also face Maccabi Haifa at home in the final qualifying round of the Europa League on Thursday, which means an under-23 team is likely to take on Chelsea on Tuesday.
Holders Manchester City will travel to Burnley, while Everton will host West Ham United. Newport County have a home tie against Newcastle United, who notched their record away win when thrashing Morecambe 7-0 on Wednesday night.
Liverpool vs. Arsenal
Burnley vs. Manchester City
Brentford vs. Fulham
Everton vs. West Ham
Aston Villa vs. Stoke City
Tottenham vs. Chelsea
Newport County vs. Newcastle United
Brighton vs. Manchester United
The fourth round will be played on Tuesday to Thursday next week, with select matches available in the U.S. on ESPN+.