Liverpool will host Everton in the third round of the FA Cup and Manchester United will travel to Wolves as Premier League teams enter the competition, with matches streaming live on ESPN+ Jan. 3-6.
Other third-round matches include Chelsea vs. Nottingham Forest, holders Manchester City host Port Vale, Middlesbrough face Tottenham and Arsenal were drawn at home to Leeds United.
Liverpool and Everton will meet in the Premier League on Wednesday for the 234th edition of the Merseyside Derby, with Everton failing to win any of the previous 19. Liverpool last won the FA Cup in 2006.
Man United are up against a Wolves team that eliminated the Old Trafford side in the quarterfinals of last year's FA Cup, and Leeds' visit to the Emirates will see manager Marcelo Bielsa up against Premier League opposition.
Wayne Rooney, who was introduced as Derby player-coach on Saturday, comes up against his former England manager, Roy Hodgson, and Crystal Palace.
Boston United of the National League North, the sixth tier of English football, could face Newcastle United if they overcome Rochdale in a second-round home replay.
Full list of third-round fixtures to be played Jan. 3-6 (select ties streaming live on ESPN+):
Leicester City v. Wigan Athletic
QPR v. Swansea
Fulham v. Aston Villa
Chelsea v. Nottingham Forest
Wolverhampton Wanderers v. Manchester United
Charlton Athletic v. West Bromwich Albion
Rochdale/Boston United v. Newcastle United
Cardiff City v. Forest Green Rovers/Carlisle United
Oxford United v. Exeter City/Hartlepool United
Sheffield United v. AFC Fylde
Southampton v. Huddersfield Town
Liverpool v. Everton
Bristol City v. Shrewsbury Town
AFC Bournemouth v. Luton Town
Brighton & Hove Albion v. Sheffield Wednesday
Bristol Rovers/Plymouth Argyle v. Coventry City/Ipswich Town
Eastleigh/Crewe Alexandra v. Barnsley
Manchester City v. Port Vale
Middlesbrough v. Tottenham Hotspur
Reading v. Blackpool
Watford v. Tranmere Rovers
Preston North End v. Norwich City
Millwall v. Newport County
Crystal Palace v. Derby County
Rotherham United v. Hull City
Brentford v. Stoke City
Fleetwood Town v. Portsmouth
Arsenal v. Leeds United
Gillingham v. West Ham United
Burton Albion v. Northampton Town
Burnley v. Peterborough United
Birmingham City v. Blackburn Rovers
Information from Reuters was used in this story.