Wirral-born referee Mike Dean is to take charge of his first ever Liverpool match in the Premier League in Monday's Merseyside derby at Everton.
Dean, who reportedly supports local club Tranmere Rovers, has also not taken charge of an Everton game since January 2006, when he sent off Everton striker Duncan Ferguson and Wigan forward Jason Roberts in a 1-1 draw. His only other Everton assignment was the club's 3-2 loss at Manchester United on Boxing Day 2003.
The only time Dean has officiated a Liverpool game was the Reds' 2-1 League Cup semifinal first-leg defeat at Sheffield United in January 2003.
The Wirral is an area that sits partially in Merseyside and partially in Cheshire, and Dean became the first ever referee to be removed from duty for an FA Cup final when Liverpool faced West Ham in 2006, with the Football Association saying: "The fact he is from the Wirral might lead to comment and debate which could place him under undue additional pressure.
"The decision has been taken with the best interests of Mike Dean and the competition in mind."
Dean's appointment comes after Manchester-born Anthony Taylor, who is reported to support non-league side Altrincham, was put in charge of Liverpool's match at home to Manchester United earlier this season.
Jose Mourinho said ahead of the game that "somebody with intention is putting such a pressure on [Taylor] that I feel it will be difficult for him to have a very good performance," which led to the FA fining the United boss and warning him as to his future conduct.
The match ended in a 0-0 draw without any significant controversy.