France coach Didier Deschamps has left Alexandre Lacazette and Samuel Umtiti out of his squad for September's Euro 2020 qualifiers against Albania and Andorra, but Aymeric Laporte is in line to win his first cap.
Arsenal forward Lacazette, 28, has not featured for France since November 2017, while 2018 World Cup winner Umtiti was involved in June but faces competition for minutes and fitness issues with Barcelona.
Speaking shortly after naming his latest squad, Deschamps said that it is not the best moment to include Umtiti.
"I have not forgotten what he has brought to this team," he said. "His position has become harder over the past six months. He is no longer an undisputed starter and he has physical issues.
"It was a tough decision, but we must look forward -- not backwards. However, the door is always open."
Manchester City defender Laporte, 25, is included after being overlooked on numerous occasions and Deschamps said his City form played a big role.
"I hope he is happy to be here," Deschamps said. "He is playing for a big club and performing well -- like last year. If he is here, it is to the detriment of others, who are not in the best sporting positions."
Manchester United striker Anthony Martial misses out after picking up an injury against Crystal Palace at the weekend.
There was also a first call-up for Lille forward Jonathan Ikone.
"With Kylian, it is Kylian, Deschamps said. "I cannot deny that I would have liked to have him available, like others.
"This is his first muscular injury. He is a player who is stringing seasons together, as well as international matches, and only had a short holiday.
"It is never ideal and there is never a good time to get hurt, but at least he will have the chance to recharge his batteries a bit."
On Dembele, Deschamps was critical about his unprofessional approach to his fitness away from the pitch.
"His situation is a factual one," he said. "He has missed many games over the past two seasons through numerous injuries -- a lot.
"After a serious operation, you need to care for your body. This is the case for all young players, who sometimes have trouble understanding that there are things to do before matches and training and thing not to do. All are required at the highest level."
Deschamps also called up Nabil Fekir after his summer move from Lyon to Real Betis, as well as Wissam Ben Yedder after he returned to Ligue 1 with Monaco after a spell with Sevilla in Spain, while he expressed his delight at Antoine Griezmann's start to life with Barcelona as he prepares to lead the attack without Mbappe.
"His Camp Nou debut was great," Deschamps said. "I had no doubts over his ability, nor his attitude. He is a very generous player, so it is great for any team to have him. He will adapt to the players and teammates he is with. He has everything he needs to succeed there."