Napoli cruised to a 5-0 win over Serie B side Virtus Entella in a friendly on Thursday.
An Alessandro Iacobucci own goal under pressure from Manolo Gabbiadini gifted Napoli the lead.
It stayed 1-0 until shortly after half-time, when Dries Mertens scored twice in a 10-minute span.
Lorenzo Insigne lobbed the keeper to add a fourth goal one minute after Mertens' second, then turned provider for David Lopez to wrap up the scoring.
Cyril Thereau scored a hat trick to help Udinese to a 6-0 win over Feldkirchen in Austria.
Edenilson also scored twice after Gabriele Angella's opener for the Serie A club.
A Goran Pandev brace led Genoa to a 3-0 win at Lucchese with Leonardo Pavoletti also on the scoresheet.
Cagliari defeated Pistoiese 3-0 while fellow newly promoted side Pescara ran out 5-0 winners over San Nicolo.
Sergio Escudero's 58th-minute goal was all Sevilla needed to hand Bundesliga side Mainz a 1-0 defeat in Germany.
Celta Vigo rallied from an early deficit to beat Real Valladolid 2-1 through Theo Bongonda and Josep Sene goals.
Hernan Perez scored the winner for Espanyol in a 2-1 victory at Almere City after Leo Baptistao's opener.
Eibar eased to a 3-1 win over Qatari club Lekhwiya in Austria, with Unai Elgezabal, Pere Milla and Jordi Calavera providing the goals for the Basque side.