Lucas Leiva will be allowed to leave Liverpool after falling out of favour with manager Brendan Rodgers.
The Reds are prepared to listen to offers of around £8m for the 28-year-old, whose first-team chances at Anfield will be severely limited if he stays, sources have told ESPN FC.
Lucas did not travel with the squad to Stoke for Liverpool's 1-0 win in the opening match of the Premier League season on Sunday.
The Brazil international has effectively been demoted to fifth choice in the battle for central-midfield places in a summer reshuffle of the squad that followed last season's failure to qualify for the Champions League.
Captain Jordan Henderson and new signing James Milner started at Stoke, with Emre Can appearing as a second-half substitute.
Joe Allen is also considered to be ahead of Lucas in the contest for selection, but is set to be out until early September with a hamstring injury.
Lucas joined Liverpool from Brazilian club Gremio for £5m in 2007, becoming a popular figure with the Anfield fanbase after a difficult start to his career on Merseyside.
He does have the option to stay, as his contract runs until 2017, but is aware he will have to leave in order to play regular football.
Inter Milan have been linked with a move for the midfielder, having tried to sign him in January.