Liverpool have announced that Joe Gomez has suffered a fracture to his lower left leg and is set to be sidelined for around six weeks.
Gomez was carried off on a stretcher in the first half of Liverpool's 3-1 victory at Burnley on Wednesday night.
The defender was assessed by Liverpool's medical staff on Thursday, where scans confirmed a fracture.
"Liverpool can confirm Joe Gomez sustained a fracture to the lower left leg during the 3-1 win at Burnley on Wednesday night," a statement on the club's website said.
"Initial indications suggest the 21-year-old is facing a spell of up to six weeks out of action, though it's dependent on how his treatment and rehabilitation programmes progress."
Gomez went down following a challenge from Burnley's Ben Mee -- one of a number of tackles that left Liverpool manager Jurgen Klopp unhappy.
"You get the ball, nice, but it's like bowling because you get the player as well," Klopp said at a news conference after the match.
"It happened four or five times, everybody likes it, but Joe is injured, and probably not only a little bit."
Gomez, who operates as a centre-back or right-back, has been one of Liverpool's best performers this season, making 18 appearances in all competitions.