Netherlands will be without captain Arjen Robben for their World Cup qualifiers against Belarus and France, coach Danny Blind has confirmed.
Blind said the Bayern Munich winger had told him "he does not feel fit just yet" after suffering a succession of injury problems.
Netherlands had hoped that the 32-year-old would be able to play a part in the matches despite having suffered a minor rib injury as he made a first start for almost seven months in the Bundesliga draw at Cologne.
He missed large parts of last season with an adductor muscle injury and has been out of action with a hamstring strain this season.
"I spoke to Arjen this morning. He's not coming -- he's not fit and that is unfortunate," Blind told a news conference.
"We will have to do without him. That is now clear, and we know where we stand. He does just not feel fit yet. We knew it would be difficult for him.
"We hoped that we could take advantage of that extra quality he brings. Unfortunately that is not the case."
Speaking after the Cologne match, Bayern coach Carlo Ancelotti had said the injury was "nothing serious, and in two or three days he'll be OK."
Blind added that he hoped Galatasaray midfielder Wesley Sneijder would be able to play despite a recent thigh problems.