Chelsea will face Dynamo Kiev in the Europa League round-of 16, with London rivals Arsenal drawn against French club Rennes.
Maurizio Sarri's side, who beat Swedish side Malmo 3-0 on Thursday to progress 5-1 on aggregate, face the 15-time Ukrainian champions in the first leg at Stamford Bridge on March 7.
The Gunners, who beat BATE Borisov in the last round, take on Rennes, 11th in Ligue 1, and are also at home in the first leg.
Europa league round of 16 draw:
Chelsea vs. Dynamo Kiev
Eintracht Frankfurt vs. Inter Milan
Dinamo Zagreb vs. Benfica
Napoli vs. Salzburg
Valencia vs. Krasnodar
Sevilla vs. Slavia Prague
Arsenal vs. Rennes
Zenit vs. Villarreal